Transformation of the common wart into squamous cell carcinoma in a patient with primary lymphedema.
Identifieur interne : 00F848 ( Main/Exploration ); précédent : 00F847; suivant : 00F849Transformation of the common wart into squamous cell carcinoma in a patient with primary lymphedema.
Auteurs : W B Shelley ; M G WoodSource :
- Cancer [ 0008-543X ] ; 1981.
Descripteurs français
- KwdFr :
- MESH :
- anatomopathologie : Carcinome épidermoïde, Transformation cellulaire néoplasique, Verrues.
- Adulte, Canal anal, Doigts, Femelle, Humains, Lymphoedème, Orteils, Verrues, Vulve, États précancéreux.
English descriptors
- KwdEn :
- MESH :
- complications : Lymphedema, Precancerous Conditions, Warts.
- pathology : Carcinoma, Squamous Cell, Cell Transformation, Neoplastic, Warts.
- Adult, Anal Canal, Female, Fingers, Humans, Toes, Vulva.
Abstract
A patient is reported in whom treatment-resistant periungual and subungual warts underwent malignant transformation into squamous cell carcinoma. Similar changes were observed in multiple warts of the vulvar, perianal, and intravaginal as well as cervical area. The tumors that develop were in many instances microinvasive but did not metastasize. The remarkable conversion of a common wart into a squamous cell carcinoma further implicates the human papovavirus in oncogenesis. The specific factors accountable for the malignant change remain completely unknown, but the patient's lymphedema praecox, as well as her severe reaction to vaccinia, and her development of a disseminate systemic Mycobacterium scrofulaceum infection suggest that the critical factor may be one of immunity.
PubMed: 7248909
Affiliations:
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Le document en format XML
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<author><name sortKey="Wood, M G" sort="Wood, M G" uniqKey="Wood M" first="M G" last="Wood">M G Wood</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Anal Canal</term>
<term>Carcinoma, Squamous Cell (pathology)</term>
<term>Cell Transformation, Neoplastic (pathology)</term>
<term>Female</term>
<term>Fingers</term>
<term>Humans</term>
<term>Lymphedema (complications)</term>
<term>Precancerous Conditions (complications)</term>
<term>Toes</term>
<term>Vulva</term>
<term>Warts (complications)</term>
<term>Warts (pathology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Canal anal</term>
<term>Carcinome épidermoïde (anatomopathologie)</term>
<term>Doigts</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphoedème ()</term>
<term>Orteils</term>
<term>Transformation cellulaire néoplasique (anatomopathologie)</term>
<term>Verrues ()</term>
<term>Verrues (anatomopathologie)</term>
<term>Vulve</term>
<term>États précancéreux ()</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Carcinome épidermoïde</term>
<term>Transformation cellulaire néoplasique</term>
<term>Verrues</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Lymphedema</term>
<term>Precancerous Conditions</term>
<term>Warts</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Carcinoma, Squamous Cell</term>
<term>Cell Transformation, Neoplastic</term>
<term>Warts</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Anal Canal</term>
<term>Female</term>
<term>Fingers</term>
<term>Humans</term>
<term>Toes</term>
<term>Vulva</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Canal anal</term>
<term>Doigts</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphoedème</term>
<term>Orteils</term>
<term>Verrues</term>
<term>Vulve</term>
<term>États précancéreux</term>
</keywords>
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<front><div type="abstract" xml:lang="en">A patient is reported in whom treatment-resistant periungual and subungual warts underwent malignant transformation into squamous cell carcinoma. Similar changes were observed in multiple warts of the vulvar, perianal, and intravaginal as well as cervical area. The tumors that develop were in many instances microinvasive but did not metastasize. The remarkable conversion of a common wart into a squamous cell carcinoma further implicates the human papovavirus in oncogenesis. The specific factors accountable for the malignant change remain completely unknown, but the patient's lymphedema praecox, as well as her severe reaction to vaccinia, and her development of a disseminate systemic Mycobacterium scrofulaceum infection suggest that the critical factor may be one of immunity.</div>
</front>
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<name sortKey="Wood, M G" sort="Wood, M G" uniqKey="Wood M" first="M G" last="Wood">M G Wood</name>
</noCountry>
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